Ectodermal Dysplasia: Familial Report of Six Cases


Ashwani Rani S. R.
Shobha Bijjaragi
Girish Suragimath
Prasad Kulkarni
Arun Kulkarni
Anand Nimbal


Ectodermal dysplasia is a hereditary disease characterized by a congenital dysplasia of one or more ectodermal structures and their accessory appendages. There are two main types, Hypohidrotic/Christ-Seimens-Tourian Syndrome and Hidrotic/Clouston syndrome. Common manifestations include defective hair follicles and eyebrows, frontal bossing with prominent supraorbital ridges, nasal bridge depression and protuberant lips. Intraorally common findings are anodontia or hypodontia and conical shaped teeth. The patient may suffer from dry skin, hyperthermia and unexplained high fever because of the deficiency of sweat glands. The present article reports unique case series of ectodermal dysplasia cases in two families, where three generations in the both the families were affected.


How to Cite
S. R., A. R., Bijjaragi, S., Suragimath, G., Kulkarni, P., Kulkarni, A., & Nimbal, A. (2014). Ectodermal Dysplasia: Familial Report of Six Cases. International Journal of Medical and Dental Sciences, 3(2), 507–511.


  1. Nunn JH, Carter NE, Gillgrass TJ, Hobson RS, Jepson NJ, Meechan JG, et al. The interdisciplinary management of hypodontia: background and role of paediatric dentistry. Br Dent J 2003;194:245–51.
  2. Vieira KA, Teixeira MS, Guirado CG, Gaviao MB. Prosthodontic treatment of hypohidrotic ectodermal dysplasia with complete anodontia: case report. Quintessence Int 2007;38:75–80.
  3. Freiman A, Borsuk D, Barankin B, Sperber GH, Krafchik B. Dental manifestations of dermatologic conditions. J Am Acad Dermatol 2009;60:289–98.
  4. Berg D, Weingold DH, Abson KG, Olsen EA. Sweating in ectodermal dysplasia syndromes: A review. Arch Dermatol. 1990;126:1075–9.
  5. Tarjan I, Gabris K, Rozsa N. Early prosthetic treatment of patients with ectodermal dysplasia: A clinical report. J Prosthet Dent 2005;93:419-24.
  6. Lamartine J. Towards a new classification of ectodermal dysplasias. Clin Exp Dermatol 2003;28:351-5.
  7. Murdock S, Lee JY, Guckes A, Wright JT. A costs analysis of dental treatment for ectodermal dyslasia. J Am Dent Assoc 2005;136:1273-6.
  8. Crawford PJ, Aldred MJ, Clarke A, Tso MS. Rapp-Hodgkin syndrome: An ectodermal dysplasia involving the teeth, hair, nails and palate. Report of a case and review of the literature. Oral Surg Oral Med Oral Pathol 1989;67:50-62.
  9. Ramos V, Giebink DL, Fisher JG, Christensen LC. Complete dentures for a child with hypohidrotic ectodermal dysplasia: A clinical report. J Prosthet Dent 1995;24:32931.
  10. Jain V, Prakash H. Prosthodontic rehabilitation for ectodermal dysplasia patients. J Indian Soc Pedo Prev Dent 2000;18:54-8.

Most read articles by the same author(s)