Metformin beyond Diabetes

##plugins.themes.academic_pro.article.sidebar##

Published Jan 31, 2020
https://doi.org/10.18311/ijmds/2020/24644
Download
Statistic

Downloads

Download data is not yet available.
Volume 9, Issue 1, January 2020

##plugins.themes.academic_pro.article.main##

Arshiya Sehgal
Department of Pharmacology, Government Medical College, Patiala - 147001, Punjab
Vijay Kumar Sehgal
Department of Pharmacology, Government Medical College, Patiala - 147001, Punjab

Abstract

No Abstract.

##plugins.themes.academic_pro.article.details##

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite
Sehgal, A., & Sehgal, V. K. (2020). Metformin beyond Diabetes. International Journal of Medical and Dental Sciences, 9(1), 1800–1802. https://doi.org/10.18311/ijmds/2020/24644
Crossref
Scopus
Google Scholar
Europe PMC

References

  1. Bailey CJ. Metformin: Historical Overview. Diabetolgia. 2017; 60:1566-76. https://doi.org/10.1007/s00125-0174318-z. PMid:28776081.
  2. Kahn BB, Alquier T, Carling D, Hardie DG. AMP activated protein kinase: Ancient energy gauge provides dues to modern understanding of metabolism. Cell Metab. 2005; 1(1):15-25.
  3. https://doi.org/10.1016/j.cmet.2004.12.003. PMid: 16054041.
  4. Pollak MN. Investigating Metformin for cancer prevention and treatment: The end of beginning. Cancer Discov. 2012; 2:778-90. https://doi.org/10.1158/2159-8290.CD-12-0263. PMid: 22926251.
  5. Laurence L Brunton, Rande Hilal Dandan, Bjorn C Knolmann. Goodman and Gilman’s -The pharmacological Basis of Therapeutics, Endocrine pancreas and pharmacotherapy of Diabetes Mellitus and Hypoglycaemia, 13 edition, New Delhi, McGraw Hill Education; Ch-47, pp. -875.
  6. Vasamsetti SB, Karnewar S, Kanugula AK, Thatipalli AR, Kumar JM, Kotamraju S. Metformininhibits monocyte to macrophage differentiation via AMPK mediated inhibition of STAT 3 activation: Potential role in atherosclerosis. Diabetes. 2015; 64:2028-41. https://doi.org/10.2337/db141225. PMid: 25552600.
  7. Cole BK, Keller SR, Wu R, Carter JD, Nadler JL, Nunemaker CS. Valsartan protects pancreatic islets and adipose tissue from inflammatory and metabolic consequences of a high fat diet in mice. Hypertension. 2010, 55:715-21. https://doi.org/10.1161/HYPERTENSIONAHA.109.148049. PMid: 20100990, PMCid: PMC2836256.
  8. Grant PJ. Beneficial effects of metformin on haemostasis and vascular function in man. Diabetes Metab. 2003; 29:6544-52. https://doi.org/10.1016/S1262-3636(03)72787-6.
  9. Faure P, Rossini E, Wiernsperger N, Richard MJ, Favier A, Halimi S. An insulin sensitizer improves the free radical defense system potential and insulin sensitivity in high fructose fed rats. Diabetes. 1999; 48(2):353-57. https://doi.org/10.2337/diabetes.48.2.353. PMid: 10334313.
  10. Kahn SE, Haffner SM, Heu MA, Herman WH, Holman RR, Jones NP, Kravitz BG, et al. Glycaemic durability of rosiglitazone, metformin or glyburide monotherapy. N. Eng. J. Med. 2006; 355(23):2427-43. https://doi.org/10.1056/NEJMoa066224. PMid: 17145742.
  11. Wu RR, Zhao JP, Jin H, Shaw P, Fang MS, Guo XF, He YQ, et al. Lifestyle intervention and metformin for treatment of antipsychotic induced weight gain: A randomised controlled trial. JAMA. 2008; 299(2):185-93. https://doi.org/10.1001/jama.2007.56-b.
  12. Glueck CJ, Fontaine RN, Wang P, Subbiah MT, Weber K, Ilug E, Streicher P, et al. Metformin reduces weight, centripetal obesity, insulin, leptin and low density lipoprotein cholesterol in non-diabetic, morbidly obese subjects with body mass index greater than 30. Metabolism. 2001; 50(7):856-61.
  13. https://doi.org/10.1053/meta.2001.24192. PMid: 11436194.
  14. Cappelli C, Rotondi M, Pirola I, Agosti B, Gandossi E, Ventiniu U, De Martino E, et al. TSH lowering effects of metformin in type 2 diabetesmellituspatients: Differencesbetweeneuthyroid, untreated hypothyroid and euthyroid on L-T4 therapy patients. Diabetes Care. 2009; 32(9):1589-90.
  15. https://doi.org/10.2337/dc09-0273 PMid: 19502536, PMCid: PMC2732148.
  16. Santomauro Junior AC, Ugolini MR, Santomauro AT, Souto RP. Metformin and AMPK: An old drug and new enzyme in the context of metabolic syndrome. Arq. Bras. Endocrinol. Metabol. 2008; 52(1):120-25. https://doi.org/10.1590/S0004-27302008000100017. PMid: 18345405.
  17. Kinlaw WB, Marsh B. Adiponectin and HIV - lipodystrophy: Taking HAART. Endocrinol. 2004; 145(2):484-86. https://doi.org/10.1210/en.2003-1513. PMid: 14739152.
  18. Shaw RJ, Lamia KA, Vasquez D, Koo SH, Bandeesy N, Depinitio RA, Montminy M, et al. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science. 2005; 310(5754):1642-46. https://doi.org/10.1126/science.1120781. PMid: 16308421. PMCid: PMC3074427.
  19. Lan B, Zhang J, Zhang P, Zhang W, Yang S, Lu D, Li W, et al. Metformin suppresses CRC growth by including apoptosis via ADOR 1. Front Bio. Sci. 2017; 22:248-57. https://doi.org/10.2741/4484. PMid: 27814614.

Most read articles by the same author(s)